30th Bernese Sleep-Wake-Epilepsy Day
The brainstem plays a fundamental role in the control of sleep, arousal, movement and breathing. Its interconnected neural circuits shape sleep–wake transitions, underlie crucial physiological features of REM sleep, and maintain vital respiratory and autonomic functions. Disruption of these systems can contribute to disorders ranging from cataplexy and REM sleep behaviour disorder to abnormal movements during sleep and central sleep apnoea.
The brainstem is increasingly recognized as a key structure in epilepsy. Impaired recovery of arousal, breathing and autonomic function after seizures may contribute to sudden unexpected death in epilepsy (SUDEP), a rare but fatal complication of epilepsy. Brainstem pathways are also therapeutically relevant, as they mediate important effects of vagus nerve stimulation, an established treatment for drug-resistant epilepsy.
The 30th Bernese Sleep-Wake-Epilepsy Day brings together leading clinicians and neuroscientists to explore this remarkable region - from fundamental mechanisms of sleep and neuromodulation to their relevance for neurological disease and treatment.
Organisation: Prof. A. Adamantidis, Prof. C. Bassetti, Prof. M. Baud, PD A. Brill, Prof. U. Fischer, Dr. C. Friedrichs-Maeder, Prof. Th. Geiser, PD C. Gutierrez Herrera, Prof. A. Klein, Prof. K. Schindler, PD M. Schmidt, Dr. A. Seiler, Prof. L. Tarokh, Prof. A. Tzovara
Program
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09.00–09.05 |
Welcome |
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Moderation: Markus Schmidt |
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09.05–09.35 |
Brainstem Dynamics Regulating REM Sleep |
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09.35–10.05 |
Neuromodulatory Regulation of Infraslow Sleep Microstructure across Aging |
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10.05–10.35 |
Noradrenergic Control of Brain Dynamics |
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10.35–11.00 |
Coffee Break |
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11.00–11.30 |
Cataplexy and REM Sleep Behavior Disorder (RBD): Two Sides of the Same Coin? |
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11.30–11.45 |
8th Bernese Sleep Award |
Award Presentation: Markus Schmidt |
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11.45–12.30 |
REM Sleep Still Paradoxical? Sensory Disconnection and Synaptic Homeostasis during Sleep |
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12.30–14.00 |
Lunch |
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Moderation: Anne-Kathrin Brill |
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14.00–14.30 |
From Twitches to Jerks beyond RBD: Brainstem Motor Phenomena in Sleep |
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14.30–15.00 |
Central Sleep Apnea – From Premature Birth to Adolescence |
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15.00–15.30 |
Coffee Break |
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Moderation: Maxime O. Baud |
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15.30–16.00 |
Interaction between Arousal Reactivity and Central Control of Breathing in the Pathophysiology of SUDEP |
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16.00–16.15 |
6th Bernese Epilepsy Award With generous support of the Kernen Fonds |
Award Presentation: Cecilia Friedrichs-Maeder |
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16.15–17.00 |
The Mechanism of Action of the Vagus Nerve, Focus on the Brainstem |
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17.00 |
Aperitif |